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Obstetrical#medications#hemorrhage#postpartumPGY 1/2/3/4

Uterotonics Reference

Pitocin, Methergine, Hemabate, Misoprostol, TXA — doses, contraindications, and use notes for postpartum hemorrhage.

Source: OB Days handoff

  • Pitocin: IV 10–40 units per 500–1000 mL as continuous infusion. 10 U IM.
  • Methergine: 0.2 mg IM q2h. HTN relative contraindication.
  • Hemabate: 250 mcg IM, q15m, up to 8 times. Asthma absolute contraindication. Administer with lomotil to mitigate diarrhea.
  • Misoprostol: 600 mcg buccal. Longer onset of action — should not be main response to hemorrhage.
  • Not uterotonic: TXA 1 g (can redose once after 30 minutes).

Referenced by handoffs